GNAO1 European Conference 2020
Online 1-3 October 2020

Famiglie GNAO1 will host the second GNAO1 European Conference online from 1-3 October 2020.

Principal objectives of the 2020 conference:

  • Facilitate cross-pollination of research ideas and developments across the globe
  • Continue to build a centre of innovative GNAO1 research and practice in the European Union
  • Generate awareness, so that GNAO1 patients and their families are able to arrive at the proper diagnosis and establish the appropriate clinical and rehabilitation programme as early as possible

The 2020 conference, which will bring together speakers and families from the Americas and Europe, will be structured as follows:

Day 1: GNAO1 research project updates (Register)
Day 2: researcher and clinician roundtable
Day 3: clinical and rehabilitation updates (Register)

All presentations will be in English. Famiglie GNAO1 will provide English-to-Italian translations.

The Programme

1 October 2020 | Research Updates

Start time 5PM CEST | 4PM BST | 11AM EDT | 8AM PDT


Insights into GNAO1 function in the brain and pathogenic mechanisms of its disease variants
Kirill Martemyanov | Scripps Research Institute (Jupiter, FL, USA)

GNAO1 encephalopathy: molecular etiology and animal models
Vladimir Katanaev | University of Geneva (Geneva, CH)

Modelling GNAO1-related diseases in Caenorhabditis elegans
Simone Martinelli, Martina Di Rocco | Italian National Institute of Health (Rome, IT)

The use of induced pluripotent stem cell technology in studies of GNAO1 related disorders
Frank Baas | Leiden University (Leiden, NL)

Early development of antisense oligonucleotide therapeutics to treat G203R GNAO1 encephalopathy
Timofei Zatsepin | Skolkovo Institute of Science and Technology (Moscow, RU)

Moderator: Luca Battistini | Santa Lucia Foundation (Rome, IT)

2 October 2020 | Round table (invitation only)

Enza Maria Valente | University of Pavia (Pavia, IT)
Renzo Guerrini | Meyer Children’s Hospital (Florence, IT)

3 October 2020 | Clinical - Rehabilitation

Start time 5PM CEST | 4PM BST | 11AM EDT | 8AM PDT



GNAO1 Natural History Study
Amy Viehoever | Washington University in St. Louis (St. Louis, MO, USA)

GNAO1 related disorders: update on clinical spectrum
Vincenzo Leuzzi, Serena Galosi | Sapienza University of Rome (Rome, IT)

Preliminary results of the GNAO1 International Registry
Erika Axeen | University of Virginia (Charlottesville, VA, USA)

Update on treatment options in GNAO1-associated movement disorder
Giovanna Zorzi | Foundation I.R.C.C.S Carlo Besta Neurological Institute (Milan, IT)

Eye-tracking for communication skills assessment and training in GNAO1 patients: a single center experience
Alessandro Capuano | Bambino Gesù Children’s Hospital (Rome, IT)
Alice Bergonzoli | Sirio Medical (Rome, IT)

Occupational Therapy strategies for children affected by GNAO1 gene mutation
Karen Balk | Washington University in St. Louis (St. Louis, MO, USA)

Moderator: Jane Yoo | Famiglie GNAO1 APS (Rome, Italy)